Pernicious Anemia – Symptoms and Treatment Options

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Pernicious anemia is a critical condition that occurs when body stops absorbing enough vitamin B12, which is of great importance to our body. In particular cells that line up stomach lose their ability to produce enough substance named Intrinsic Factor, which causes this critical condition. To matter of fact intrinsic factor is important as it is an ideal combination of vitamin B12 to form B12 intrinsic factor so that digestive system can absorb it. Vitamin B12 is also well known as cobalamin, which plays vital role in several processes in human body. So if you are going through any such agony, it may be among worst blood disorder to take proper care of.

Vitamin B12 helps produce red blood cells, supports nerve cell function and even helps build DNA. In case body’s immune system malfunctions and begins attacking cells in stomach, it leads to decrease in intrinsic factor, which greatly affects B12 absorption for worst. To be precise pernicious anemia is also known as megaloblastic anemia, it describes large and immature red blood cell seen in people with same condition.

Here are few pernicious anemia symptoms as mention:

  • Weakness Fatigue Numbness
  • tingling of hands and feet
  • Difficulty walking
  • Decreased appetite
  • Weight loss
  • Nausea
  • Tender, smooth tongue
  • Diarrhea
  • Irritability
  • Increased heart rate

  • Generally an abnormality in red blood cells gets normal by supplementing vitamin B12. In case pernicious anemia is detected in later stages it may cause nerve damage, numbness and tingling, which can be permanent. Usually it can be detected through routine checkups and a blood test (CBC, or cell blood count). People who are at extreme of developing the risk are elderly, strict vegetarians who don't take diet rich in vitamin B12 and pregnant women. Importantly babies been breast feed by vegetarian moms are at higher risk of developing vitamin B12 deficiency by age 4 to 6 months. Their liver reserves are normally plentiful and if gets limited can be quickly depicted quickly and can adverse growth rate.

    Remember, folate supplement is also recommended along with vitamin B12. If taken alone my indeed alleviate the anemia but allow the neurologic (nerve) deficits to progress or even accelerate. For this reason it’s imperative to take both the supplements together. This treatment generally corrects your anemic condition and if started in the early stages can also correct any neurological disorders. Problem of deficiency caused due to poor diet will require a change in diet options.


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tis amit has 187 articles online and 3 fans

Get information about blood diseases or blood disorders on online health guide- Peoples-Health. Know about various blood diseases like- pernicious anemia , Amyloidosis, Sickle Cell Anemia and more.

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Pernicious Anemia – Symptoms and Treatment Options

This article was published on 2012/03/22